NOT KNOWN FACTUAL STATEMENTS ABOUT CONOLIDINE

Here, we demonstrate that conolidine, a pure analgesic alkaloid Employed in common Chinese drugs, targets ACKR3, thus providing further proof of the correlation between ACKR3 and pain modulation and opening alternate therapeutic avenues for that remedy of chronic discomfort.The initial asymmetric full synthesis of conolidine was made by Micalizio a